IVF PGS Results

Finally met with our RE yesterday to discuss our PGS results and next steps on Peanut Satterfield journey. The past week waiting for these results has been agonizing and caused us to have some difficult conversations.

What happens if none of our embryos are normal? This was our 3rd round of IVF. We had responded well on the 2nd cycle and had a good number of embryos make it to Day 5/6. This time we had similar response but lost all but two of the embryos before Day 6. If none of the embryos are normal does that mean that my eggs are bad? Or did we just have a bad batch this IVF cycle? If we decide or are forced to do another round of IVF, we have now reached the point where we will not have any additional insurance coverage, thus we would be looking at all costs out of pocket.

Do we try reciprocal IVF and see if Heather’s eggs were normal or better responders? Would she have to loose a lot of weight before we start the process? Would my body be receptive to her embryos? Would we have to get a new donor? If not, do we look at adoption or give up on our dream to be moms.

These were all of the questions running through our mind the past week and the heartfelt emotional discussions that we had to prepare ourselves for depending on the outcome.

We got to our visit and luckily our RE had good news, we have one normal embryo!!! We all hoped that both would have been normal but we were happy to hear that we still have a chance with this cycle.

Next steps for Peanut Satterfield:
– Endometrial scratch, cervical dilation and hysterscopy next week
– Start Estradiol patches with next AF
– PIO instead of progesterone suppositories
– Transfer of normal

Let’s hope our little normal fighter is our miracle baby..

IVF Take 3

Three weeks ago we started on the journey yet again. I had mixed uneasy feelings going into this round due to our miscarriage at the end of the year. However, I tried to remain positive about the road ahead.

The weeks leading up were very stressful due to work and drama surrounding getting our medications due to a change in my work insurance carrier. After weeks of following up and escalation, I finally received my medications five days before we started stimulation. Work continued to be stressful as I am attempting to transition out of a role and the leader of that group was not too accepting of my transition. I was feeling I was already fighting many battles before my body even began to try to produce healthy follicles and embryos.

Stimulation Day 1 came and all went well. We went for our first monitoring ultrasound and I was responding well to stims with eight measurable (greater than 10mm in diameter) follicles on the right, three measurable in the left and 19 less than between my two ovaries. We continued with the same dosage and made an appointment to check again in two days. We went back for our second monitoring appointment and my body was responding well with the following follicle numbers:

  • Right: 
  • 15
  • 17
  • 13.5
  • 15.5
  • 13.5
  • 16.5
  • 17.5
  • 11
  • 17
  • 12.5
  • 10
  • 15.5
  • 12.5
  • 13.5
  • 10 less than
  • Left 
  • 17.5
  • 11.5
  • 14.5
  • 10.5
  • 14.5
  • 13
  • 11.5
  • 8 less than

Our RE was out of the office but had instructed the team that she wanted to push my body so that we could get as many follicles as possible with greater chances for more embryos to biopsy for pre-genetic screening. The team made the decision to keep our same dosage and for me to return the next day. We returned and got the following updated numbers:

  • Right:
  • 18
  • 15.5
  • 15.5
  • 13.5
  • 11
  • 19
  • 12
  • 11
  • 20.5
  • 15
  • 16.5
  • 13
  • 18.5
  • 18
  • 11
  • 5 less than
  • left:
  • 17
  • 15.5
  • 13.5
  • 16.5
  • 12.5
  • 16.5
  • 20
  • 11.5
  • 8 less than

Still progressing well, they advise I again stay with the same dose and return for what would probably be our last monitoring visit prior to trigger. We went in the next morning and our numbers were looking great and very similar to our previous cycle.  

  • Right: 
  • 17
  • 20
  • 17.5
  • 14.5
  • 13
  • 13.5
  • 16
  • 17.5
  • 18.5
  • 21.5
  • 13
  • 23
  • 16
  • 14
  • 13.5
  • 17.5
  • 12
  • 4 less than
  • left:
  • 17.5
  • 12.5
  • 15.5
  • 18.5
  • 12.5
  • 14
  • 13
  • 13
  • 23.5
  • 19
  • 15.5
  • 4 less than 

My Estradiol levels were nicely increasing but not spiking as they had with our previous cycle, so they gave us the green light to trigger and schedule the retrieval for that following Tuesday morning.  

The day before the retrieval the pain really began to set in and it was getting uncomfortable to sit or lay down. I woke up the morning of the retrieval and felt as I did with our previous cycle. I had pushed through nine days of IVF stimulation medications to hopefully grow healthy beautiful follicles that will fertilize and grow into beautiful 5-day embryos. Last year we had not previously keep the same dosage throughout to get over 20 follicles growing and ready for retrieval. Last year, I had no idea what to expect and had never experienced the pain that I felt that morning. Last year I was so upset that we were not going to be able to proceed with the next step of a fresh transfer and that we would have to freeze all of the embryos due to my high Estradiol levels. This year, I knew that a freeze all was expected due to the genetic testing.

The RE on call came into our room prior to the retrieval and was like you have been a patient here for a while, it is time for us to get you a lot of eggs and get you pregnant. No kidding dude! The retrieval went well and he was able to retrieve 23 follicles. I was in a lot of pain, but tried to keep reminding myself that it was all worth it to get our good number of embryos for biopsy.

We received the fertilization update the next day that of the 23 follicles, 15 of them were mature and 13 had fertilized. Woohoo 13 was a great number to start with. We still had to make it over the hurdle of Day 3 growth and Day 5 blastocyst stage before our embryos could be biopsied and sent off for testing.  

We got the Day 3 call and we still had a dozen embryos growing. We decided to celebrate over the weekend and wait for the Day 5 call. Day 5 came and the news was not as great as we had hoped, only one embryo had made it to the biopsy stage and we had five that were still growing, so we had lost six.  

Today the office called back to give us final numbers and unfortunately only two embryos were able to be biopsied. So after 23 we only have two to test to see if genetically my embryos are normal.

I am beyond disappointed. I feel like our window to parenthood is diminishing and that our miracle baby may not be in our cards after all. I know it only takes one embryo but based on the growth rate of our embryos I am not feeling very positive. In addition to top it all off, once I finally started to feel better from the retrieval, Aunt Flow has shown up in full force.
Now we will wait to find out the results and if this will be the end to our journey….